What is Tesamorelin?

Tesamorelin is a synthetic growth‑hormone–releasing hormone (GHRH) analogue. It is FDA‑approved to help reduce excess abdominal fat in adults with HIV‑associated lipodystrophy. By mimicking endogenous GHRH, Tesamorelin stimulates your pituitary gland to release more growth hormone and insulin‑like growth factor‑1 (IGF‑1), which supports fat metabolism, muscle preservation and overall metabolic health. Each program includes a 3‑mL vial containing 24 mg of Tesamorelin. The powder is reconstituted with a sterile diluent and self‑administered by subcutaneous injection, usually 1–2 mg per dose. You should follow your clinician’s instructions carefully and rotate injection sites to prevent irritation

Benefits of Tesamorelin:

✔ Reduces visceral fat – By elevating growth hormone and IGF‑1, tesamorelin targets deep abdominal fat and improves body composition. It is the only medication approved in the U.S. for reducing visceral fat in adults with HIV‑related lipodystrophy.

✔ Preserves lean muscle mass – Studies show tesamorelin can increase skeletal muscle area and density, helping you maintain muscle while fat is lost.

✔ Improves lipid & metabolic profiles – Clinical research reports improved lipid parameters and insulin sensitivity when visceral fat decreases.

✔ Supports cognitive & cardiovascular health – Growth hormone and IGF‑1 are linked to healthy brain function and tesamorelin’s visceral‑fat reduction may lower cardiovascular risk.

✔ Promotes skin health & recovery – Growth hormone stimulates collagen synthesis and IGF‑1 supports skin‑cell turnover, which may enhance recovery and support more youthful‑looking skin.

Who Should Use Tesamorelin?

• Adults seeking to reduce stubborn visceral fat under medical supervision.

• Individuals wanting to preserve lean muscle while improving body composition.

• Those aiming to optimize metabolism, energy and hormonal balance.

• People focusing on longevity, cognitive health or improved recovery.

• Tesamorelin is not a weight‑loss medication and is unsuitable for pregnant or breastfeeding women, individuals with active cancer, or anyone with pituitary disorders. It should only be used under a clinician’s guidance.

Stacking Options:

• Visceral fat reduction & muscle preservation: Stack with Sermorelin or Ipamorelin to enhance growth‑hormone secretion.

• Metabolic & cardiovascular support: Combine with GLP‑1 receptor agonists such as Tirzepatide for comprehensive metabolic health.

• Cognitive & anti‑aging benefits: Pair with NAD⁺ or BPC‑157 therapies to support brain function and recovery.

Always consult a Reverse provider before combining therapies.