GHK-Cu / Estriol / Niacinamide / Tretinoin Cream (30 gm)

Prescription Topical Skin Support

As skin ages, it doesn’t just lose moisture — it loses thickness, elasticity, and its ability to repair itself efficiently.

This compounded prescription cream is designed to support skin at that deeper level, not just on the surface.

This formula combines clinically studied ingredients that work together to support skin renewal, texture, hydration, and long-term resilience when used consistently.

What This Cream Is Designed to Support

This medication is commonly used by patients who notice:

• Thinner or crepey skin

• Fine lines that don’t respond to standard skincare

• Dryness that keeps coming back

• Skin that looks tired or worn down

• Diminished elasticity over time

Rather than masking these changes, this formula supports how the skin repairs and renews itself.

How It Works

Each ingredient plays a different role:

• GHK-Cu (Copper Peptide)
  Supports collagen production and skin repair, helping skin feel stronger and more resilient over time.

• Estriol (Topical, Low-Dose)
  Helps improve skin hydration and elasticity locally, especially in aging or thinning skin.

• Niacinamide (Vitamin B3)
  Supports the skin barrier, helps even tone, and reduces irritation and redness.

• Tretinoin
  Encourages healthy skin turnover and collagen production, helping smooth texture and soften fine lines with consistent use.

Together, these ingredients address multiple aspects of skin aging in one prescription formula.

How to Use

Nighttime Application Only

• Gently cleanse your face

• Apply a pea-sized amount to the treatment area

• Avoid eyes, lips, and broken skin

If you are new to prescription retinoids or have sensitive skin, start every other night for 1–2 weeks, then increase to nightly use as tolerated.

Daily sunscreen use is strongly recommended while using this product.

What to Expect

This is not an overnight product.

Most patients notice gradual changes over several weeks, such as:

• Smoother texture

• Improved hydration

• Skin that feels thicker and healthier

• Softer appearance of fine lines

• A more rested, even look

Mild dryness, flaking, or sensitivity can occur early on and usually improves as skin adjusts.

Who This Is Best For

This product is commonly chosen by patients who:

• Are in their late 30s and beyond

• Have skin that no longer responds to over-the-counter products

• Want meaningful skin improvement without procedures

• Prefer a simple, nightly routine

• Are looking for long-term skin support, not a quick cosmetic fix

How This Compares to Other Options

• Standard moisturizers: hydrate the surface but don’t change how skin functions

• Over-the-counter retinol: often weaker and less consistent

• Multiple serums: require layering and guesswork

• In-office procedures: effective but more costly and involve downtime

This prescription cream offers a consistent, at-home option that works gradually and predictably over time.

Important Notes

• For topical use only

• Avoid use during pregnancy

• Sun protection is essential

• Use only as directed

If irritation occurs, reduce frequency and contact our team if symptoms persist.

Questions?

Our nursing team is happy to help you decide if this product fits your skin goals or how to incorporate it into your current routine.